TRIDENT is a multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial of a fixed low-dose combination blood pressure (BP) lowering pill (Triple Pill) on top of standard of care, in patients with a history of acute ICH and systolic BP (SBP) levels defined as at least ‘high normal to borderline high’ (defined as ≥130 mmHg) and on either minimal or no BP lowering treatment according to standard guideline definitions.
For Health Professionals
TRIDENT is a multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial of a fixed low-dose combination blood pressure (BP) lowering pill (Triple Pill) on top of standard of care, in patients with a history of acute ICH and systolic BP (SBP) levels defined as at least ‘high normal to borderline high’ (defined as ≥130 mmHg) and on either minimal or no BP lowering treatment according to standard guideline definitions.
Clinical Trial Registration:
Project status
Participant recruitment for the TRIDENT study began in August 2017.
1500 patients with ICH will be recruited from approximately 70 centres from around the world.
TRIDENT